AgroIP

Chalcone Review

2012-01-29T08:17:00.000-08:00

Are you ready for the chalcones? The next generation of pesticides have been uncovered and brought to you by AgroIP. Before it was the ryanodine inhibitors, compounds for which are still emerging from company pipelines but for the next several years the chalcone compounds look set to take the market by storm.

Over ten companies are battling for this insecticide market as these compounds hold promise for use on not only crops but also livestock as well. It all started when a patent was filed by….

Review of ISO Names in 2011

2012-01-28T07:27:00.000-08:00

バイエル:スルホニル尿素農薬

2012-01-22T07:03:00.000-08:00

DuPont: Imidazole Fungicides

2012-01-21T07:32:00.000-08:00

住友化学：ベンゾッシアゾル農薬

2012-01-15T06:50:00.000-08:00

SYN-523

2012-01-14T08:20:00.000-08:00

バイエル: ジチヒン農薬

2012-01-08T06:04:00.000-08:00

SYRICI: Dual-Action Anthranilamides

2012-01-03T08:05:00.000-08:00

Off-Patent Products/Generics 2012

2011-12-30T08:00:00.000-08:00

This report is tracking the development of active ingredients as they come off-patent and then generic. These active ingredients have been chosen for their commercial importance and unique characteristics which will make them significant in tomorrow’s generic market.

Each monograph details:

If the product you are interested in is not listed below please enquire via email.

The monographs are available to purchase separately or several together. The monographs are available as an Adobe pdf file. Please enquire at agro_ip[at]ymail.com for prices.

ビーエーエスエフ: ジメチルフェニル農薬

2011-12-25T08:21:00.000-08:00

Syngenta: Bicyclic Difluoromethylpyrazole

2011-12-18T08:29:00.000-08:00

住友化学：新ピリダジン

2011-12-11T08:05:00.000-08:00

BASF: Trifluoromethylsulfur Fungicide

2011-12-03T22:52:00.000-08:00

バイエル: チアジアゾール殺菌剤

2011-11-27T05:43:00.000-08:00

Dow AgroSciences: Pyridine Herbicide

2011-11-20T07:53:00.000-08:00

日本農薬: 新規殺ダニ剤

2011-11-13T06:43:00.000-08:00

日本曹達: ピリジン誘導体植物病害防除剤 (update 01)

2011-11-13T06:37:00.000-08:00

ISK: Phenyl Triazoles

2011-10-23T02:19:00.000-07:00

ノバルティス：ベンズアミド殺虫剤

2011-10-08T05:35:00.000-07:00

Otsuka Chemical: Bicyclic Piperidines

2011-09-18T06:20:00.000-07:00

アグロカネショウ: 新除草剤

2011-09-06T11:25:00.000-07:00

Merial: Insecticidal 4-aminopyrimidines

2011-08-21T07:00:00.000-07:00

Pyridazine Review

2011-08-14T07:34:00.000-07:00

Anthranilamide Review

2011-08-14T05:20:00.000-07:00

Tracking 沈阳化工研究院 (update 02)

2011-07-31T08:22:00.000-07:00

This post aims to track patented pesticidal compounds at SYRICI over 2011. This aims to give competitors an insight into the discovery efforts at one of China's formidable agroscience companies.

1) Cyenopyrafen derivatives
2) Herbicidal ester compounds
3) Imazapic derivatives

This post may be downloaded here.

日本曹達: 硫黄の殺虫剤

2011-07-16T06:35:00.000-07:00

Bayer CropScience: Searching For Spiro No. 05

2011-06-26T04:04:00.000-07:00

The spiro compounds developed by Bayer have truly been ground breaking in providing new ways to tackle disease and pests. Many chemists are interested in knowing what the next spiro compound might be emerging from the Bayer pipeline but with a plethora of patents that disclose ‘spiro compounds as useful pesticides’, we take a look at two interesting molecules.

Bayer have so far research and developed four spiro compounds: spiroxamine (funigicide/trade name: Impulse), spiromesifen (insecticide/trade name: Oberon) and spirodiclofen (insecticide/trade name: Envidor) and spirotetramat insecticide/trade name: Movento). All of which are nearing the end of their proprietary lives with patents due to expire over the next several years (see generics post). This post aims to analyse which compound will take the slot of number 5 at Bayer.

Although disclosed in separate patents the results for the compounds below against the same targets have been published. Both retain the central tetramic acid structure. Whether Bayer decide to commercialize the ester forms like their predecessors remains to be seen.

In biological tests, both compounds displayed greater than 80% control of green peach aphids (Myzus persicae in cabbages), cotton aphids (Aphis gossypii) and red spider mites (Tetranychus urticae in bean plants).

DuPont: Fungicidal Piperidines (DPX-QGU42)

2011-05-22T07:33:00.000-07:00

住友化学；アロマチク殺虫剤

2011-04-30T06:55:00.000-07:00

も十年ぐらいパイロンは住友化学で研究してあります。下の化合物は殺虫剤と防虫剤使いことが出来ます。Sc1, Sc2, Sc3 はいい効果リポトをしました（チャバネゴキブリ）。

明治製菓株式会社: 新ピリパイロピン誘導体 (ME5343)

2011-04-10T09:37:00.000-07:00

Marrone: Sarmentine Analogs

2011-04-03T08:23:00.000-07:00

Sarmentine analogs have been disclosed by Marrone as useful for controlling pests, weeds and phytopathogens such as bacteria, fungi and viruses. The three compounds below are preferred compounds of the analogs presented. N-(2E,4E-decadienoyl)pyrrolidine is also called sarmentine and was first separated from the fruit of Piper sarmentosum in 1987. Sarmentine is also used as a solubilizer in hydrophobic compounds in cosmetics and pharmaceuticals.

Sarmentine demonstrates excellent control of pigweed (Amaranthus retroflexus L.), barnyard grass (Echinochloa crusgalli L.), bindweed (Convolvulus arvensis L), crabgrass (Digitaria sanguinalis L), Sprangletop (Leptochloa fascicularis Lam.), Dandelion (Taraxacum, officinale F.) and Lambsquarters (Chenopodium album L.). No results are reported for the pesticidal or fungicidal activity for the sarmentine analogs.

Phenyl Triazoles (KUI-109)

2011-03-05T11:07:00.000-08:00

Marrone: Herbicidal Thaxtomin (MBI-005)

2011-01-16T06:52:00.000-08:00

A recent patent from Marrone claims methods for controlling the germination and growth of broadleaf, sedge and grass weeds in rice using compositions of thaxtomin produced by Stremptomyces scabies, Streptomyces acidiscabies and Stremptomcyes scabeie.

In greenhouse tests thaxtomin A composition displayed 90-100% control of Echinochloa colonum, Monochoria vaginalis, Ammannia spp, Heteranthera limosa, Cyprus difformis, Sphenoclea zeylanica, Alisma-plantago aquatica and Cyprus iria in rice.

Review of ISO Names in 2010

2010-12-29T06:28:00.000-08:00

Bayer CropScience: Iodochromones

2010-12-18T09:58:00.000-08:00

The iodochromone compounds below have been investigated as fungicides by Bayer since the late 1990s. In greenhouse tests the compounds demonstrated effective control in wheat (Blumeria graminis). The compounds have been claimed in a variety of combination patents with other fungicides.

Syngenta: Phenylethyl pyrazole amides

2010-12-04T07:11:00.000-08:00

Phenyl ethyl amides have been disclosed by Syngenta as suitable compounds for the control of phytopathogenic fungi in crops a few years ago.

Compounds similar to 1001 have shown good control of Alternaria brassicae in Radish, Botrytis cinerea in cucumbers, Sphaerotheca fuliginea in Gherkins and Mycosphaerella graminicola in wheat.

The difluoromethylpyrazole amide component is also common to Bayer’s bixafen and Syngenta’s isopyrazam.

Recent claims include compositions with mandipropamid, azoxystrobin & fluopicolide for the control of Peronospora spp, Pythium spp, Pseudoperonospora spp on brassica and bulb vegetables.

アイサグロ；新しいインダンニル (IRF-135)

2010-11-28T05:42:00.000-08:00

化合物下はアイサグロの新しい殺菌剤と考えられています。特許で二つは好みである。畑の試験で麦（赤さび病）F1はいい効果を表されました。ほかの農作物つかいことが出来るはサトウキビ、コーヒー、豆、シトラス、大豆（phakopsora pachyrhizi）。請求頂では九化合物であります。

Insecticidal acetimidamides

2010-10-30T09:25:00.000-07:00

Compound 33 is of the class of acetimidamides which have been reported by KRIBB to show good efficacies against Nilaparvata lugens in rice seedlings, Myzus persicae in tobacco plants and Tetranychus urticae in kidney bean leaves. The compound would appear to occupy similar chemical space to amitraz but as reported, with greater control of pests.

ビーエーエスエフ: 新しい殺虫剤

2010-07-11T10:35:00.000-07:00

Review of ISO Names in 2009

2010-01-02T02:20:00.001-08:00

Kumiai Chemical: Pyrrolines

2009-08-16T09:00:00.000-07:00

Kumiai have patented combinations of compound KIH illustrated below with other herbicides such as fentrazamide, pyrazolsulfuron-ethyl and dymron. Although pyroline-based herbicides have been patented before, the compound illustrated below is unique in that it possesses a cyclopropyl carbonyl attached to the 1 position of the pyrroline.

KIH in mixtures with compounds such as pyrimisulfan, mefenazate, cafenstrole, indanofan exhibited good control of Echinochloa oryzicola, Monochoria vaginalis and Scirpus juncoides.

Isagro: IR7592

2009-04-26T10:41:00.000-07:00

Cocamidopropyl betaine (CAPB) is a zwitterionic surfactant made from coconut. The compound is typically used in shampoos and cosmetics. CAPB and other zwitterionic compounds have been disclosed by Isagro as useful for the control of pathogenic fungi.

In biological tests cocamidopropyl betaine demonstrated good preventative control of Plasmopara viticola on vines at 250 ppm. The compound also showed good synergistic control with other fungicides such as fosetyl-Al, tetraconazole and valiphenal for the control of the same pathogen.

한국생명공학연구원: ナフタレン- 1 ,4 -ディオネ

2009-03-03T09:49:00.000-08:00

KRIBBは特許でナフタレン- 1 ,4 -ディオネ殺虫剤取得をしました。化合物である3313同じようなはヂアアシルCoA：グリセリントランスフェラーゼ阻害されます。試験で3313はオンシツコナジラミとコナガ薬効がありました。

トマトに使うことが可能性。薬学では使用可能性と報告されていますが農学では使用や報告されていません。

University of Zhejiang: Spiromesifen Derivatives (浙江大学/浙江大學)

2009-02-16T07:19:00.001-08:00

With a only a few years of patent protection remaining on spiromesifen, an interesting patent from the University of Zhejiang looks at altering the ester functionality of spiromesifen with a dimethyl cyclopropyl unit commonly seen in pyrethroids. Compound 316 is one of the most potent compounds against Lepidoptera species illustrated therein.

Spiromesifen (Oberon/Forbid/Judo) is a spirocyclic compound discovered and developed by Bayer CropScience. Other similar compounds developed by Bayer include spirodiclofen (Envidor) and spirotetramat (Movento). Further derivatives from Bayer are also expected to be developed.

The relative ease of synthesis and major global market registrations already obtained for spiromesifen make it an attractive candidate for generic manufacturers.

日産化学：新殺虫剤

2009-01-18T09:11:00.000-08:00

化合物Aは新殺虫剤です。試験で化合物A は良いLC5O（モモアカアブラムシ）出来ました。化合物Aはシエノピラフェンの同じようです。三つはシアノエチレンを持っています。IKA-2002/IKI-2002 は石原産業会社の殺虫剤です。りんごとなしを使われます。化合物AとIKA-2002はまだ開発中です。

Review of ISO Names in 2008

2009-01-04T09:49:00.000-08:00

Isagro: Inducing Resistance...

2008-12-14T05:47:00.000-08:00

Isagro have claimed mixures of salicylic acid and its derivatives as a method for inducing resistance in plants to fight pathogenic fungi. By combining salicylic acid with other compounds reduces undesirable side effects such as crop damage.

In greenhouse tests copper (II) salt of acetylsalicylic acid and metal salts such as (FeSO4, ZnSO4) showed good preventative control of Peronospora tabacina on tobacco and Plasmopara viticola on vines. Mixtures with other organic compounds such as iprovalicarb and metiram are also claimed.

Isagro's IR6396

2008-12-11T10:11:00.001-08:00

The difluoromethoxy-pyrazole herbicide illustrated below is thought to be a new PPO inhibitor in development at Isagro. The work on this area of chemistry by Isagro dates back to the mid 1990s. Last year herbicidal combinations of this compound were claimed with other established herbicides such as amidosulfuron, clomazone, pinoxaden, penoxsulam and picolinafen.

More recently emulsifiable concentrates were disclosed as the preferred formulation type of this compound. The herbicide is further disclosed as useful for the control of weeds such as Abutilon theofrasti, Alisma plantago, Amaranthus spp, Chenopodium album,
Ipomea spp, Sinapsis arvensis in crops such as rice, wheat, barely, maize and soybeans. It is thought this compound is undergoing development under the code name IR-6396. Isagro report that IR-6396 is to be launched after 2010.

FMC's Benzimidazole Herbicide

2008-12-10T09:55:00.000-08:00

The benzimidazole compound illustrated below is thought to be a new herbicide in development at FMC. The product patent for which dates back about 10 years. In biological tests, FMC-H demonstrated good control of Giant Ragweed, Common Ragweed, Common Sunflower, Burcucumber, Common Mares-Tail, Field Bindweed, Buffalobur, Mayweed, Hedge Bindweed and Dandelions. FMC-H has also been claimed in combination with other herbicides such as hydroxamic acids and auxin herbicides.

Shenyang Research Insitute (SYRICI)

2008-12-06T03:29:00.001-08:00

Shenyang Research Institute Chemical Industry (SYRICI) is one of the major R&D centers in China to be developing new agrochemicals. Some of their compounds being developed are highlighted below. SYP-1620 is a fungicide that has been registered in China and is undergoing registration in India. This seems to be in joint development with Dow AgroSciences as Dow are the assignees of the world patent protecting this compound.
Fungicides SYP-3375 and SYP-3200 both have world patent filings and are undergoing field trials in China.
Herbicides SYP-249 and SYP-300 to have shown good control of weeds in wheat and soybeans in biological tests. SYP-300 is very similar in structure to Sumitomo Chemical’s flumioxazin.

Syngenta: Pyrazole Amides

2008-11-25T10:11:00.001-08:00

The difluromethyl-pyrazole class of compounds is a flourishing area of chemistry, with recent ISO names received for Sygenta's isopyrazam and sedaxane. Below are further candidates from Syngenta which are likely to emerge from this class of compounds.